The Hidden Risks of Using Medical Anaesthetics for Recreational Highs

Etomidate, a medical anaesthetic, is increasingly being misused for recreational purposes across Asia, often appearing in vaping devices under names like "space oil" .

What is etomidate?

Medically, etomidate is an ultra-short-acting intravenous drug used to induce anaesthesia during surgery . It works by depressing the central nervous system, which creates sedative effects . Because of its rapid onset and offset, it is typically reserved for high-risk patients in clinical settings .

The rise of recreational misuse

Reports of non-medical use have surged in several Asian countries over the last few years . Users are often vaping the substance, attracted by the same rapid effects that make it useful in medicine . Authorities have noted that much of this supply is likely produced illegally rather than diverted from hospitals .

Significant health risks

The primary medical concern with etomidate is its ability to inhibit the enzyme 11β-hydroxylase, which disrupts the body's adrenal synthesis of cortisol . This suppression can last for several hours after a single dose . Prolonged or repeated use, such as through vaping, poses serious risks to the body's hormonal balance and overall health .